UNIVERSITY OF
GUAM
COURSE OUTLINE
Course Number CH
311 College(or sponsoring unit) CAS/Natural
Sciences
Course Title Basic
Laboratory Techniques in Credit
Hours 2
Organic
Chemistry
Date of Final Approval Semester
Offered Fall
Course counts as General Education Requirement
Ö Part of Chemistry & Biology
major program
Elective
1. CATALOG DESCRIPTION:
Laboratory work in organic
chemistry with emphasis on the development of manipulative skills in such
techniques as distillations, reduced pressure fractionations, chromatography,
and crytallizations, and constructions of apparatus utilized in the
preparations, purification, identification and study of simple organic compounds.
Six hours laboratory. Prerequisite: Concurrent with CH 310a.
2. COURSE CONTENT:
1. Introduction
2. Laboratory Safety and Waste Disposal.
3. Crystallization. Macroscale and Microscale Crystallization
and Impure Acetanilide (containing sand, charcoal, and a few traces of aniline
- brief handout).
4. Melting Points and Boiling Points.
Melting points of Pure Acetanilide, and Phthalic Acid. Determination of Unknown
with Mixed Melting Point.
5. Distillation. Macroscale and Microscale
Simple Distillation. Microscale Fractional Distillation. Instant Microscale
Distillation.
6. Steam Distillation. Macroscale - Steam
Distillation of 0-nitrophenol from p-n itrophenol.
7. Extraction. Extraction of Caffeine from
Tea. Distribution Coefficient of Benzoic Acid (Microscale).
8. Sublimation of Caffeine.
9. Thin-Layer Chromatography. Separation
of Food Color (green, yellow, red, blue) using paper chromatography. (Handout)
10. Column Chromatography. Microscale.
Separation of two dyes: methyl orange and methyl blue. (Handout)
11. The 5N2 Reaction. Macroscale - Synthesis
of 1-Bromobutane.
3. RATIONALE
FOR THE COURSE:
The basic laboratory technique
course is a required course for chemistry and biology majors. It is intended
for students to:
- familiarize themselves with laboratory safety
rules.
- learn basic lab techniques in the macroscale
and microscale synthesis of
organic compounds.
- develop and acquire theoretical understanding
in lab techniques and
experimental procedures.
- be able to record lab procedures and observations
in the lab notebook.
4. SKILLS
AND BACKGROUND REQUIRED OR EXPECTED:
This course requires a background
in general chemistry and a concurrent enrollment in CH 310a Organic Chemistry.
5. TEACHING
METHODOLOGIES AND ANTICIPATED CLASS SIZE:
Two three-hour laboratory.
material included in the text will be supplemental with the lecture discussion
with emphasis on theory and lab techniques. Anticipated class size: 15-20
students.
6. ADDITIONAL
COURSE DESCRIPTORS:
None.
7. LEARNING OBJECTIVES FOR STUDENTS:
At the end of the course, the
student should be able to:
- be familiar with laboratory and safety rules.
- know basic lab techniques in the macroscale and
microscale synthesis of
organic compounds
- have a good theoretical understanding in lab
techniques and experimental
procedures.
- be able to record lab procedures and
observation.
8. METHODS OF EVALUATION:
Quizzes and one final exam (30%),
laboratory experiments and reports (60%) and personal evaluation including
neatness, attendance, affitude, etc. (10%).
9.
REQUIRED AND RECOMMENDED TEXTS
ANDIOR STUDY GUIDES:
Kenneth L. Williamson, Macroscale
and Microscale Organic ExDeriments. 1989, D.C. Heath and Company.
Handouts for additional
experiments.
10. SUBSEQUENT
COURSES:
CH 312 Laboratory Techniques in
Organic Chemistry CHIBI 419 Biochemistry and BI 416 Cellular Physiology. This
one-semester course also provides a basic knowledge in lab techniques for
students preparing for technical training in natural sciences or laboratory
work.
THE CALENDAR OF
ASSIGNMENTS, ATTENDANCE AND GRADING POLICIES ARE TO BE INCLUDED IN THE COURSE
SYLLABUS